5'-Highly Hydrophobic Protecting Group in the Rapid Separation of Automatic-Synthesis Oligonucleotides.
نویسندگان
چکیده
منابع مشابه
comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.
heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
15 صفحه اولSynthesis of Oligonucleotides Carrying 5 ’ - 5 ’
--------------------------------------------------------------------------------------------------------There is considerable interest in coupling oligonucleotides to molecules and surfaces. Although aminoand thiol-containing oligonucleotides are being successfully used for this purpose, cycloaddition reactions may offer greater advantages due to their higher chemoselectivity and speed. In this...
متن کاملThe synthesis of oligonucleotides containing a primary amino group at the 5'-terminus.
Oligonucleotides containing a primary amino group at their 5'-termini have been prepared and further derivatised with amino specific probes. The sequence required is prepared using standard solid phase phosphoramidite techniques and an extra round of synthesis is then performed with N-monomethoxytrityl-0-methoxydiisopropylaminophosphinyl 3-aminopropan(1)ol. After cleavage from the resin, remova...
متن کاملEmploying a hydrophobic-bentonite as a highly efficient and versatile catalyst for a green one-pot and rapid synthesis of 4H-benzo-[b]-pyran derivatives
A hydrophobic-bentonite catalyst (cetyltrimethyl ammonium bromide-bentonite) has been used as a very mild, neutral, eco-friendly, reusable, non-toxic, low-cost and easily available catalyst. It was prepared by replacing the exchangeable Na+ cations of a homoionic Na–bentonite with cetyltrimethyl ammonium bromide (CTMAB) cations. The catalyst was characterized by XRD, BET and SEM. The...
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ژورنال
عنوان ژورنال: Analytical Sciences
سال: 1992
ISSN: 0910-6340,1348-2246
DOI: 10.2116/analsci.8.3